Antineoplastic Alkylating Agent

Preferred Label : Antineoplastic Alkylating Agent;

NCIt synonyms : Chemotherapy Alkylators; Chemotherapy Alkylating Agents;

NCIt definition : An antineoplastic agent that replaces hydrogen atom(s) in nucleophilic moieties with alky radical(s), hindering proper function. Alkylating agents exhibit cytotoxic effects through the alkylation of DNA, resulting in strand cross-linking, ultimately inhibiting DNA replication and cancer cell growth.;

Details

Origin ID

C1590;

UMLS CUI

C0282532;

Currated CISMeF NLP mapping
- antineoplastic agents, alkylating [MeSH Descriptor]
- antineoplastic agents, alkylating [MeSH concept]
Semantic type(s)
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- antineoplastic agents, alkylating [MeSH concept]
- antineoplastic agents, alkylating [MeSH Descriptor]

Keyword's position in hierarchy(ies) :

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