Light and Heavy Chain Deposition Disease

Preferred Label : Light and Heavy Chain Deposition Disease;

NCIt synonyms : LHCDD;

NCIt definition : A subtype of monoclonal immunoglobulin deposition disease in which heavy and light chains deposition results in non-amyloid tissue deposits which may cause organ dysfunction.;

Neoplastic status : Undetermined;

NCI Metathesaurus CUI : CL950969;

Details

Origin ID

C158965;

UMLS CUI

C5204117;

Currated CISMeF NLP mapping
- Light and heavy chain deposition disease [ICD-11 Sub-sub category]
- Light and heavy chain deposition disease [ORDO Disease]
Disease excludes abnormal cell
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
Disease excludes normal cell origin
- Myeloid Cell [NCIt concept]
- Precursor B-Lymphoblast [NCIt concept]
Disease may have findings
- Monoclonal Gammopathy [NCIt concept]
- Neoplastic Plasma Cells Present in Bone Marrow [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Amyloid Deposition [NCIt concept]
- Apple Green Dichromism Present in Polarized Congo-Red Stained Sections [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
disease_has_finding
- Immunoglobulin Deposition [NCIt concept]
- Immunoglobulin Heavy Chain Deposition [NCIt concept]
- Immunoglobulin Light Chain Deposition [NCIt concept]
disease_has_normal_cell_origin
- B-Lymphocyte [NCIt concept]
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Mature B-Lymphocyte [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Hematopoietic and Lymphatic System [NCIt concept]
- Lymphatic System [NCIt concept]
disease_may_have_associated_disease
- Congestive Heart Failure [NCIt concept]
- Monoclonal Gammopathy of Undetermined Significance [NCIt concept]
- Multiple Myeloma [NCIt concept]
- Nephrotic Syndrome [NCIt concept]
- Renal Failure [NCIt concept]

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