Preferred Label : Levofloxacin;
NCIt synonyms : Levofloxacin Hydrate; 7H-Pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic Acid, 9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-,
Hydrate (2:1), (S)-; (S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido(1,2,3-de)-1,4-benzoxazine-6-carboxylic
Acid Hydrate (2:1);
NCIt definition : A broad-spectrum, third-generation fluoroquinolone antibiotic and optically active
L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the
bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II),
an enzyme required for DNA replication, RNA transcription, and repair of bacterial
DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.;
Alternative definition : NCI-GLOSS: A substance used to treat bacterial infections. It belongs to the family
of drugs called quinolone antibiotics.;
UNII : 6GNT3Y5LMF;
InChIKey : SUIQUYDRLGGZOL-RCWTXCDDSA-N;
CAS number : 138199-71-0;
Drug name : Quixin; Levaquin;
Chemical formula : 2C18H20FN3O4.H2O;
Codes from synonyms : CDR0000044906; 307;
Origin ID : C1586;
UMLS CUI : C0282386;
Currated CISMeF NLP mapping
- Semantic type(s)
- UMLS correspondences (same concept)
- concept_is_in_subset
