Polidocanol - CISMeF

Preferred Label : Polidocanol;

NCIt synonyms : Dodecylnonaoxyethylene Glycol Monoether; Laureth-9; Nonaethylene Glycol Monododecyl Ether; Lauromacrogol 400; Laureth 9;

NCIt definition : An alkyl polyglycol ether of lauryl alcohol with sclerosing and potential antineoplastic activities. Upon intralesional administration, polidocanol induces endothelial cell injury by disrupting calcium signaling and nitric oxide pathways. Following endothelial damage, platelets aggregate at the site of injury and attach to the venous wall, resulting in a dense network of platelets, cellular debris, and fibrin that occludes the vessel. Inducing endothelial cell damage within melanoma metastases may incite an antitumor response in untreated bystander lesions and inhibit the growth of in transit metastases and other cutaneous lesions.;

UNII : 0AWH8BFG9A;

CAS number : 3055-99-0;

Drug name : Aethoxysklerol; Asclera;

NCI Metathesaurus CUI : CL563467;

Details

Origin ID

C158511;

UMLS CUI

C0071330;

Currated CISMeF NLP mapping
- Lauromacrogol 400 [SMS substance]
- Lauromacrogol 400 (substance) [SNOMED CT concept]
- Polidocanol [ICD-11 Extension code]
- Polidocanol [MeSH Descriptor]
- Polidocanol [ICHI extension code]
- polidocanol [MeSH concept]
See also inter- (CISMeF)
- Product containing lauromacrogol 400 (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Lauromacrogol 400 (substance) [SNOMED CT concept]
- Polidocanol [ICD-11 Extension code]
- Polidocanol [MeSH Descriptor]
- Product containing lauromacrogol 400 (medicinal product) [SNOMED CT concept]
- polidocanol [ATC Code]
- polidocanol [MeSH concept]
Validated automatic mappings to BTNT
- polidocanol [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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