Polidocanol - CISMeF

Preferred Label : Polidocanol;

NCIt synonyms : Dodecylnonaoxyethylene Glycol Monoether; Laureth-9; Nonaethylene Glycol Monododecyl Ether; Lauromacrogol 400; Laureth 9;

NCIt definition : An alkyl polyglycol ether of lauryl alcohol with sclerosing and potential antineoplastic activities. Upon intralesional administration, polidocanol induces endothelial cell injury by disrupting calcium signaling and nitric oxide pathways. Following endothelial damage, platelets aggregate at the site of injury and attach to the venous wall, resulting in a dense network of platelets, cellular debris, and fibrin that occludes the vessel. Inducing endothelial cell damage within melanoma metastases may incite an antitumor response in untreated bystander lesions and inhibit the growth of in transit metastases and other cutaneous lesions.;

UNII : 0AWH8BFG9A;

CAS number : 3055-99-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 3055-99-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Aethoxysklerol; Asclera;

NCI Metathesaurus CUI : CL563467;

Details

Origin ID

C158511;

UMLS CUI

C0071330;

Automatic exact mappings (from CISMeF team)
- Nonaethylene Glycol Monododecyl Ether [MeSH concept]
- Polidocanol [ICHI extension code]
Currated CISMeF NLP mapping
- 3,6,9,12,15,18,21,24,27-nonaoxanonatriacontan-1-ol [Substance BNPC]
- Polidocanol [ICD-11 Extension code]
- Polidocanol [MeSH Descriptor]
- dodecylnonaoxyethylene glycol monoether [MeSH Supplementary Concept]
- dodecylnonaoxyethylene glycol monoether [MeSH concept]
- polidocanol [MeSH concept]
See also inter- (CISMeF)
- Lauromacrogol 400 (substance) [SNOMED CT concept]
- dodecyl alcohol, ethoxylated [Substance BNPC]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Lauromacrogol 400 (substance) [SNOMED CT concept]
- Polidocanol [ICD-11 Extension code]
- Polidocanol [MeSH Descriptor]
- Product containing lauromacrogol 400 (medicinal product) [SNOMED CT concept]
- dodecyl alcohol, ethoxylated [Substance BNPC]
- dodecylnonaoxyethylene glycol monoether [MeSH Supplementary Concept]
- polidocanol [ATC Code]
- polidocanol [MeSH concept]
Validated automatic mappings to BTNT
- polidocanol [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt Antineoplastic Agent Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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