Preferred Label : Autologous Dendritic Cell/Myeloma Fusion Vaccine;
NCIt synonyms : Autologous DC/Multiple Myeloma Fusions; DC/Multiple Myeloma Fusions; DC/MM Fusions; DC/Plasma Cell Myeloma Fusion; DC/MM Fusion Vaccine;
NCIt definition : A therapeutic cancer vaccine consisting of autologous dendritic cells (DCs) fused
with patient-derived plasma cell (multiple) myeloma cells with potential immunostimulatory
and antineoplastic activities. Upon administration, autologous DC/multiple myeloma
fusions stimulate both helper and cytotoxic T-lymphocyte (CTL) responses through the
presentation of internalized and newly synthesized tumor associated antigens (TAAs).
This may promote cellular and humoral antitumor immune responses in patients with
plasma cell myeloma.;
NCI Metathesaurus CUI : CL938016;
Origin ID : C158480;
UMLS CUI : C4764251;
Semantic type(s)
- concept_is_in_subset
