Fibronectin Type III Domain-Containing Protein 5 - CISMeF
Fibronectin Type III Domain-Containing Protein 5NCIt concept
Preferred Label : Fibronectin Type III Domain-Containing Protein 5;
NCIt synonyms : Fibronectin Type III Domain Containing Protein 5; FNDC5; Fibronectin Type III Repeat-Containing Protein 2;
NCIt definition : Fibronectin type III domain-containing protein 5 (212 aa, 24 kDa) is encoded by the
human FNDC5 gene. This protein plays a role in the cellular response to physical reactivity.;
NCIt note : Following removal of the signal peptide, fibronectin type III domain-containing protein
5 is cleaved C-terminally after amino acid residue 143, which removes the transmembrane
microbody targeting signal, yielding the secreted protein irisin. (UniProt);