" /> Fibronectin Type III Domain-Containing Protein 5 - CISMeF





Preferred Label : Fibronectin Type III Domain-Containing Protein 5;

NCIt synonyms : Fibronectin Type III Domain Containing Protein 5; FNDC5; Fibronectin Type III Repeat-Containing Protein 2;

NCIt definition : Fibronectin type III domain-containing protein 5 (212 aa, 24 kDa) is encoded by the human FNDC5 gene. This protein plays a role in the cellular response to physical reactivity.;

NCIt note : Following removal of the signal peptide, fibronectin type III domain-containing protein 5 is cleaved C-terminally after amino acid residue 143, which removes the transmembrane microbody targeting signal, yielding the secreted protein irisin. (UniProt);

NCI Metathesaurus CUI : CL937842;

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31/07/2025


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