" /> Pimodivir - CISMeF





Preferred Label : Pimodivir;

NCIt definition : An orally bioavailable non-nucleoside inhibitor of the polymerase basic protein 2 (PB2) subunit of the influenza A virus polymerase complex with potential antiviral activity. Upon administration, pimodivir occupies the 7-methyl GTP (m7GTP) binding site of PB2, thereby blocking the cap-snatching activity of the influenza polymerase complex and inhibiting the synthesis of viral mRNA. PB2 is one of three subunits that make up the influenza A viral polymerase complex, which is responsible for replication and transcription of the viral RNA (vRNA) genome in the nuclei of infected cells.;

UNII : DFC121MXC3;

InChIKey : JGPXDNKSIXAZEQ-SBBZOCNPSA-N;

CAS number : 1629869-44-8;

Molecule name : VX-787; JNJ 63623872; VX 787; JNJ-63623872;

NCI Metathesaurus CUI : CL937691;

Détails


Position du mot-clé dans l'(les) arborescence(s) : arborescence

Vous pouvez consulter :


Nous contacter.
27/07/2025


[Accueil] [Haut de page]

© CHU de Rouen. Toute utilisation partielle ou totale de ce document doit mentionner la source.