Preferred Label : Umbilical Cord Blood-derived CD4 /CD25 T-regulatory Cells CK0801;
NCIt synonyms : CK-0801; UCB-derived CD4 CD25 Tregs CK0801;
NCIt related terms : CK-0802;
NCIt definition : A preparation composed of allogeneic umbilical cord blood (UCB)-derived, ex vivo expanded
and enhanced CD4 /CD25 T-regulatory cells (Tregs) with potential immunomodulatory
activity. Upon administration, the UCB-derived CD4 /CD25 Tregs CK0801 may promote
immunologic homeostasis and prevent autoimmunity by suppressing self-reactive T-cells.
This may induce tolerance to allogeneic organ transplants, prevent graft-versus-host
disease (GvHD), and suppress autoimmune pathology.;
UNII : H7DFT9JF6M;
Molecule name : CK0801; CK 0801;
NCI Metathesaurus CUI : CL937693;
Origin ID : C158084;
UMLS CUI : C4764035;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
