Preferred Label : Gallium Ga 68 NODAGA-CBP8;
NCIt synonyms : [68Ga]CBP8; Gallium-68 NODAGA-CBP8; [68Ga]CBP-8; 68Ga-CBP8;
NCIt related terms : CBP-8 GALLIUM GA-68;
NCIt definition : A radiotracer composed of CBP8, a collagen-targeting peptide, linked via a tris(tert-butyl)
ester-protected 1,4,7-triazacyclononane,1-glutaric acid-4,7-acetic acid (NODAGA) chelator,
to the radioisotope gallium Ga 68, with potential imaging activity upon positron emission
tomography/computed tomography (PET/CT). Upon administration, gallium Ga 68 NODAGA-CBP8
selectively binds with high affinity to collagen type 1. Upon PET/CT imaging, gallium
Ga 68 NODAGA-CBP8 can be used to detect lung fibrosis, which is characterized by excess
deposition of collagens, primarily type 1 collagen, and other extracellular matrix
proteins in the parenchyma.;
UNII : W4K4DZ2XVU;
CAS number : 1846556-19-1;
NCI Metathesaurus CUI : CL937224;
Origin ID : C157635;
UMLS CUI : C4763760;
Semantic type(s)
- concept_is_in_subset
- has_target
