Preferred Label : Emtricitabine/Tenofovir Disoproxil Fumarate;
NCIt synonyms : FTC/TDF;
NCIt definition : A fixed combination of emtricitabine, a nucleoside reverse transcriptase (RT) inhibitor
(NRTI) analog of cytidine, and tenofovir disoproxil fumarate, an NRTI analog of adenosine
monophosphate, that is used to treat human immunodeficiency virus (HIV) infection.
Upon oral administration, emtricitabine and tenofovir inhibit the activity of HIV
RT by competing with natural deoxyribonucleosides for incorporation into the growing
viral DNA chain resulting in early chain termination. This interferes with the generation
of DNA copies of viral RNA, which is necessary for the synthesis of new virions.;
Drug name : Truvada;
NCI Metathesaurus CUI : CL937093;
Origin ID : C157535;
UMLS CUI : C1608323;
See also inter- (CISMeF)
- Semantic type(s)
- concept_is_in_subset
