Preferred Label : CD56-enriched CD3-positive Donor Lymphocytes;
NCIt synonyms : CD56-enriched Donor Cells; CD56 /CD3 Donor Cells; CD56-enriched Donor Lymphocytes;
NCIt definition : A population of CD3-positive lymphocytes expressing the CD56 surface antigen, with
potential immunomodulating activity. Upon infusion of the CD56-enriched CD3-positive
donor lymphocytes, these cells may facilitate the reconstitution of CD4-positive T-cells,
regulatory T-cells (Tregs) and natural killer (NK) cells, which may reduce the incidence
of post-transplant graft-versus-host disease (GvHD) following haploidentical stem
cell transplant (SCT). CD56 is a transmembrane glycoprotein also known as neural cell
adhesion molecule 1 (NCAM-1).;
NCI Metathesaurus CUI : CL937067;
Origin ID : C157500;
UMLS CUI : C4763664;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
