GCGR wt Allele

Preferred Label : GCGR wt Allele;

NCIt synonyms : GGR; Glucagon Receptor wt Allele; GL-R;

NCIt definition : Human GCGR wild-type allele is located in the vicinity of 17q25.3 and is approximately 10 kb in length. This allele, which encodes glucagon receptor protein, is involved in hormone-dependent signaling. Mutation of the gene is associated with type 2 diabetes mellitus and glucagon cell hyperplasia and neoplasia.;

NCI Metathesaurus CUI : CL937079;

GenBank Accession Number : U03469;

Details

Origin ID

C157479;

UMLS CUI

C4761349;

Automatic exact mappings (from CISMeF team)
- global genome nucleotide-excision repair [GO term]
- glucagon receptor [ORDO Gene]
OMIM relation
- Glucagon receptor [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 17q25.3 [NCIt concept]
gene_involved_in_pathogenesis_of_disease
- Glucagon Cell Hyperplasia and Neoplasia [NCIt concept]
gene_is_element_in_pathway
- Neuroactive Ligand-Receptor Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients