Delamanid - CISMeF

Preferred Label : Delamanid;

NCIt synonyms : Imidazo(2,1-b)oxazole, 2,3-Dihydro-2-methyl-6-nitro-2-((4-(4-(4-(trifluoromethoxy)phenoxy)-1-piperidinyl)phenoxy)methyl)-, (2R)-;

NCIt definition : A nitro-dihydro-imidazooxazole derivative, with antimycobacterial activity. Upon oral administration, delamanid, a prodrug, is activated via the mycobacterial F420 coenzyme system to form a reactive intermediate metabolite that inhibits the synthesis of the mycobacterial cell wall components methoxy-mycolic and keto-mycolic acid. This leads to the depletion of these cell wall components and destruction of mycobacteria.;

UNII : 8OOT6M1PC7;

InChIKey : XDAOLTSRNUSPPH-XMMPIXPASA-N;

CAS number : 681492-22-8;

Drug name : Deltyba;

Molecule name : OPC-67683; OPC 67683;

Chemical formula : C25H25F3N4O6;

NCI Metathesaurus CUI : CL937142;

Details

Origin ID

C157406;

UMLS CUI

C3489682;

Automatic exact mappings (from CISMeF team)
- OPC-67683 [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- Delamanid [LOINC component]
- Delamanid [ICD-11 Extension code]
- Delamanid [SMS substance]
- Delamanid (substance) [SNOMED CT concept]
- delamanid [MeSH concept]
See also inter- (CISMeF)
- Product containing delamanid (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Delamanid [LOINC component]
- Delamanid (substance) [SNOMED CT concept]
- Product containing delamanid (medicinal product) [SNOMED CT concept]
- delamanid [ATC Code]
- delamanid [MeSH concept]
Validated automatic mappings to BTNT
- delamanid [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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