Monoclonal Gammopathy of Renal Significance - CISMeF
Monoclonal Gammopathy of Renal SignificanceNCIt concept
Preferred Label : Monoclonal Gammopathy of Renal Significance;
NCIt synonyms : MGRS;
NCIt definition : A condition caused by a B-cell or plasma cell clone resulting in the deposition of
the secreted monoclonal immunoglobulin, without evidence for overt lymphoma or myeloma.
This category includes a wide spectrum of renal pathology and include such lesions
as immunoglobulin-associated amyloidosis, the monoclonal immunoglobulin deposition
diseases (MIDDs; light chain deposition disease, heavy chain deposition disease, and
light and heavy chain deposition disease), proliferative glomerulonephritis with monoclonal
immunoglobulin deposits (PGNMID), C3 glomerulopathy with monoclonal gammopathy, light
chain proximal tubulopathy (Fanconi syndrome), and several others.;