Liposomal Amphotericin B

Preferred Label : Liposomal Amphotericin B;

NCIt synonyms : Amphotericin B-Lipid Complex; Amphotericin B Liposomal; Lipid Complex, Amphotericin B; AmBisome; L-AMB;

NCIt definition : A liposome-encapsulated formulation of the polyene antifungal antibiotic amphotericin B produced by the bacterium Streptomyces nodosus with antifungal activity. Amphotericin B binds to ergosterol, an essential component of the fungal cell membrane, and alters cell membrane integrity, resulting in leakage of intracellular components and cell rupture. This agent may also induce oxidative damage in fungal cells and has been reported to stimulate host immune cells. Compared to amphotericin B alone, liposomal delivery of amphotericin B allows for a greater drug concentration in target tissues while decreasing systemic side effects.;

Drug name : Abelcet;

Molecule name : DKF-5122;

Details

Origin ID

C1566;

UMLS CUI

C1145701;

Automatic exact mappings (from CISMeF team)
- AMPHOTERICINE B, LIPOSOME [SMS substance]
- Amphotericin B liposome (product) [Inactive SNOMED CT concept]
- Lamb - meat (substance) [SNOMED CT concept]
- amphotericin B lipid complex [MeSH concept]
- lipoarabinomannan [MeSH Supplementary Concept]
Currated CISMeF NLP mapping
- AmBisome [MeSH concept]
- Amphotericin B liposome (substance) [SNOMED CT concept]
- liposomal amphotericin B [MeSH concept]
- liposomal amphotericin B [MeSH Supplementary Concept]
False automatic mappings
- Lamb [LOINC component]
See also inter- (CISMeF)
- Amphotericin B lipid complex (substance) [SNOMED CT concept]
- Amphotericin b lipid complex [SMS substance]
Semantic type(s)
- Antibiotic [UMLS semantic type]
- Organic Chemical [UMLS semantic type]
UMLS correspondences (same concept)
- Amphotericin B liposome (product) [Inactive SNOMED CT concept]
- Amphotericin B liposome (substance) [SNOMED CT concept]
- liposomal amphotericin B [MeSH Supplementary Concept]
- liposomal amphotericin B [MeSH concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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