Dexverapamil Hydrochloride

Preferred Label : Dexverapamil Hydrochloride;

NCIt synonyms : Verapamil Hydrochloride, ( )-; R-Verapamil Hydrochloride; Verapamil (R)-form Hydrochloride; R Verapamil Hydrochloride;

NCIt definition : The R-enantiomer of the calcium channel blocker verapamil. Dexverapamil competitively inhibits the multidrug resistance efflux pump P-glycoprotein (MDR-1), thereby potentially increasing the effectiveness of a wide range of antineoplastic drugs which are inactivated by MDR-1 mechanisms. This agent exhibits decreased calcium antagonistic activity and toxicity compared to racemic verapamil. (NCI04);

UNII : B0P742MK5O;

InChIKey : DOQPXTMNIUCOSY-HZPIKELBSA-N;

CAS number : 38176-02-2;

NCI Metathesaurus CUI : CL563167;

NSC code : 632821;

Details

Origin ID

C156452;

UMLS CUI

C4744832;

Currated CISMeF NLP mapping
- Lekoptin [International Nonproprietary Name]
- Verapamil hydrochloride [SMS substance]
- Verapamil hydrochloride (substance) [SNOMED CT concept]
- verapamil hydrochloride [MeSH concept]
- verapamil hydrochloride [Substance BNPC]
- verapamil hydrochloride [SNOMED Notion]
See also inter- (CISMeF)
- verapamil [MeSH Descriptor]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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