Chimeric Monoclonal Antibody 81C6

Preferred Label : Chimeric Monoclonal Antibody 81C6;

NCIt synonyms : ch81c6;

NCIt definition : A chimeric, murine-human monoclonal antibody directed against the tumor-associated antigen (TAA) tenascin (hexabrachion) that may, when conjugated with a radioisotope, be useful in radiotherapy or radioimaging. Tenascin, an extracellular matrix glycoprotein is upregulated in certain pathological conditions such as infection, inflammation and tumor growth, and is highly expressed in the tumor microenvironment in some malignancies.;

NCI Metathesaurus CUI : CL563141;

Details

Origin ID

C156351;

UMLS CUI

C4744763;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- GDC Terminology [NCIt concept]
- GDC Therapeutic Agent Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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