Preferred Label : Partially HLA-matched AdV/CMV/EBV-specific Allogeneic T-Lymphocytes;
NCIt synonyms : Partially HLA-matched AdV/CMV/EBV-specific Allogeneic T-cells; Partially HLA-matched Adenovirus/Cytomegalovirus/Epstein-Barr Virus-specific Allogeneic
Cytotoxic T-Lymphocytes; Allogeneic Partially HLA-matched AdV/CMV/EBV-specific T-cells; Allogeneic HLA-matched Virus-specific T-cell Lines; Allogeneic HLA-matched VSTs;
NCIt definition : Partially or closely human leukocyte antigen (HLA)-matched allogeneic cytotoxic T-lymphocytes
(CTLs), derived from cell lines, specifically reactive to the three human viruses
adenovirus (AdV), cytomegalovirus (CMV) and Epstein-Barr virus (EBV), with potential
antiviral activity. Upon infusion of the partially HLA-matched AdV/CMV/EBV-specific
allogeneic T-lymphocytes in immunocompromised patients or upon allogeneic hematopoietic
stem cell transplantation (HSCT) in an immunodeficient recipient, these CTLs may kill
AdV, CMV, and/or EBV-infected cells, and may prevent or reduce the severity of viral
infections by these pathogens.;
NCI Metathesaurus CUI : CL562982;
Origin ID : C156256;
UMLS CUI : C4744691;
Semantic type(s)
- Cell [UMLS semantic type]
- concept_is_in_subset
