Gontivimab - CISMeF

Preferred Label : Gontivimab;

NCIt synonyms : RSV-specific Nanobody ALX-0171; Anti-RSV F Nanobody ALX-0171; Anti-RSV Protein F Nanobody ALX-0171;

NCIt definition : A trivalent nanobody composed of three monovalent Nb017 moieties linked with glycine-serine (GS) linkers, directed against the fusion protein (F protein) of human respiratory syncytial virus (RSV), with potential activity against RSV infections. Upon administration via nebulization and inhalation, gontivimab targets and binds to RSV F protein, neutralizing the virus, and preventing viral entry into host cells. RSV F protein is a small envelope glycoprotein required for cytopathic syncytia formation that results from cell-to-cell fusion.;

UNII : DY8W536BUY;

CAS number : 1257358-38-5;

Molecule name : ALX 0171; ALX-0171;

NCI Metathesaurus CUI : CL562895;

Details

Origin ID

C156058;

UMLS CUI

C5418255;

CISMeF manual mappings
- Anti-(human respiratory syncytial virus fusion glycoprotein F), immunoglobulin Lama glama single chain VH-VH-VH, trivalent monoclonal antibody [SMS substance]
Currated CISMeF NLP mapping
- gontivimab [MeSH Supplementary Concept]
- gontivimab [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- gontivimab [MeSH Supplementary Concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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