ATAC-Seq - CISMeF

Preferred Label : ATAC-Seq;

NCIt synonyms : Assay for Transposase-Accessible Chromatin Using Sequencing; Assay for Transposase-Accessible Chromatin Sequencing; Assay for Transposase Accessible Chromatin with High-Throughput Sequencing;

NCIt related terms : ATAC-seq (assay for Transposase-Accessible Chromatin (ATAC) strategy is used to study genome-wide chromatin accessibility);

NCIt definition : A molecular genetic technique that isolates and sequences chromosomal regions that are rich in open chromatin. First, nuclei are harvested from a cellular sample. Then a hyperactive Tn5 transposase is added to the nuclei where it excises non-nucleosomal DNA strands and ligates co-administered high-throughput sequencing adapters (tagmentation). The tagged DNA fragments are isolated, amplified by PCR and sequenced. The number of reads for specific region of DNA correlate with increased chromatin accessibility and this method can identify regions of transcription factor and nucleosome binding.;

NCI Metathesaurus CUI : CL562893;

Détails

Origin ID

C156056;

UMLS CUI

C4744539;

Automatic exact mappings (from CISMeF team)
- Chromatin Immunoprecipitation Sequencing [MeSH Descriptor]
- assay for transposase-accessible chromatin using sequencing [OBI concept]
Currated CISMeF NLP mapping
- ATAC-Seq [MeSH concept]
Semantic type(s)
- Molecular Biology Research Technique [UMLS semantic type]
concept_is_in_subset
- CTDC Value Terminology [NCIt concept]
- GDC Terminology [NCIt concept]
- GDC Value Terminology [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

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