Preferred Label : TP53 Negative;
NCIt synonyms : Tumor Protein p53 Negative; p53 Loss; TP53 Tumor-Suppressor Gene Inactivation; Tumor Suppressor p53 Negative; Cellular Tumor Antigen p53 Negative; Transformation-Related Protein 53 Negative; Antigen NY-CO-13 Negative; TRP53 Negative; p53 Negative; TP53 Loss;
NCIt definition : An indication that TP53 expression or activity has not been detected in a sample.;
NCIt note : This finding is most often associated with a two-hit genetic mechanism involving deletion
of one allele of the TP53 gene and a loss-of-function mutation in the other allele.;
NCI Metathesaurus CUI : CL562901;
Origin ID : C156049;
UMLS CUI : C4744534;
Semantic type(s)
- concept_is_in_subset
- related_to_genetic_biomarker
