Frontal Lobe Anaplastic Astrocytoma

Preferred Label : Frontal Lobe Anaplastic Astrocytoma;

NCIt definition : An anaplastic astrocytoma occurring in the frontal lobe.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL562889;

Details

Origin ID

C156035;

UMLS CUI

C4744520;

Disease excludes abnormal cell
- Poorly Differentiated Neoplastic Astrocyte [NCIt concept]
Disease may have findings
- Headache [NCIt concept]
- Motor Manifestations [NCIt concept]
- Seizure [NCIt concept]
- Sensory Manifestations [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Excludes anatomical site(s)
- Spinal Cord [NCIt concept]
Has associated anatomic sites
- Brain [NCIt concept]
- Central Nervous System [NCIt concept]
- Cerebral Hemisphere [NCIt concept]
- Nervous System [NCIt concept]
- Supratentorial Brain [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Grade 4 Lesion [NCIt concept]
- Indolent Clinical Course [NCIt concept]
- Microvascular Proliferation [NCIt concept]
- Necrotic Change [NCIt concept]
- Precise Histogenesis Unknown [NCIt concept]
disease_has_abnormal_cell
- Anaplastic Astrocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Astrocyte [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Glial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell [NCIt concept]
- Neoplastic Neuroepithelial Cell and Neoplastic Perineural Cell [NCIt concept]
disease_has_finding
- Anaplastic Lesion [NCIt concept]
- Diffuse Pattern [NCIt concept]
- High Grade Lesion [NCIt concept]
- Increased Cellularity Present [NCIt concept]
- Infiltrative Growth Pattern [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Mitotic Activity [NCIt concept]
- Nuclear Atypia [NCIt concept]
disease_has_grade
- Grade 3 [NCIt concept]
- High Grade [NCIt concept]
disease_has_normal_cell_origin
- Astrocyte [NCIt concept]
- Glial Cell [NCIt concept]
- Neuroepithelial Cell [NCIt concept]
- Neuron, Neuroepithelial Cell, and Supporting Cell of the Nervous System [NCIt concept]
disease_has_normal_tissue_origin
- Nerve Tissue, Neuroepithelial Tissue, and Nerve Sheaths [NCIt concept]
- Neuroepithelial Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Brain [NCIt concept]
- Central Nervous System [NCIt concept]
- Cerebral Hemisphere [NCIt concept]
- Frontal Lobe [NCIt concept]
disease_mapped_to_gene
- TP53 Gene [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Loss of Chromosome 6 [NCIt concept]
disease_may_have_molecular_abnormality
- CDKN2A Gene Deletion [NCIt concept]
- PTEN Gene Inactivation [NCIt concept]
- RB1 Gene Inactivation [NCIt concept]
- TP53 Gene Inactivation [NCIt concept]

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