" /> Grade 4 Hypoxic Ischemic Encephalopathy, AE - CISMeF





Preferred Label : Grade 4 Hypoxic Ischemic Encephalopathy, AE;

NCIt synonyms : Grade 4 HIE, AE; Grade 4 Hypoxic Ischemic Encephalopathy, Adverse Event;

NCIt related terms : Grade 4 Hypoxic Ischemic Encephalopathy;

NCIt definition : An adverse event in a newborn characterized by severe clinical signs (see Sarnat stages for further guidance on mild, moderate and severe clinical signs of encephalopathy) of encephalopathy resulting from a perinatal asphyxia event with life-threatening consequences (e.g. respiratory depression, refractory seizures).;

Alternative definition : INC: Severe clinical signs* of encephalopathy resulting from a perinatal asphyxia event with life-threatening consequences (e.g. respiratory depression, refractory seizures). Note: *see Sarnat stages for further guidance on mild, moderate and severe clinical signs of encephalopathy.;

NCI Metathesaurus CUI : CL555778;

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09/05/2025


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