Recombinant OX40 Ligand

Preferred Label : Recombinant OX40 Ligand;

NCIt synonyms : OX40 ligand; OX40L; Therapeutic OX40 Ligand;

NCIt definition : A recombinant agent, which is chemically identical to or similar to the endogenous protein Fas ligand OX40, a member of the tumor necrosis factor (TNF) family. Expressed by antigen presenting cells (APC), OX40 ligand binds to the OX40 receptor on CD4 T-cells, thereby priming antigen-specific activation of CD4 T-cells and inducing CD4 T-cell secretion of interleukin 4 (IL-4). (NCI04);

Details

Origin ID

C1548;

UMLS CUI

C1527028;

Automatic exact mappings (from CISMeF team)
- TNF superfamily member 4 [ORDO Gene]
- Tumor necrosis factor ligand superfamily, member 4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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