NCIt definition : The cryptophycins are a family of 16-membered macrolide antimitotic agents isolated
from the cyanobacteria Nostoc sp. The mechanism of anticancer activity of the cryptophycins
has been associated with their destabilization of microtubules and induction of bcl-2
phosphorylation leading to apoptosis. Cryptophycins demonstrated activity against
the wide spectrum of solid tumors including those that overexpress the multidrug resistance
efflux pump P-glycoprotein. (NCI);
UNII : XO974V2M5T;
CAS number : 124689-65-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 124689-65-2
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