Preferred Label : Topical Fibrinogen-depleted Human Standardized Platelet Lysate CAM-101;
NCIt synonyms : FD hPL CAM-101; Ophthalmic Fibrinogen Depleted Allogeneic Standardized Human Platelet Lysate; Topical Fibrinogen Depleted Human Platelet Lysate;
NCIt definition : A topical ophthalmic drop formulation containing fibrinogen-depleted, standardized
human platelet lysate which is derived from pooled human platelet lysates (phPL) collected
from healthy human donors, that can potentially be used to treat dry eye disease (DED).
Upon ophthalmic administration of the topical fibrinogen-depleted human platelet lysate
CAM-101, CAM-101 serves as artificial tears to relieve ocular dryness. In addition,
as CAM-101 is rich in various growth factors and contains numerous nutritive, anti-inflammatory
and pro-regenerative components, the components in CAM-101 may abrogate the underlying
processes, such as inflammation, that contribute to DED. Compared to autologous serum
drops that are used as artificial tears, CAM-101 is a more shelf-stable, convenient
and standardized formulation.;
Molecule name : CAM-101; CAM 101;
NCI Metathesaurus CUI : CL555330;
Origin ID : C154531;
UMLS CUI : C4733628;
Semantic type(s)
concept_is_in_subset