NCIt synonyms : Mutated in Multiple Advanced Cancers 1 Deficiency; Phosphatase and Tensin Homolog Deficiency; TEP1 Deficiency; Phosphatidylinositol 3,4,5-Trisphosphate 3-Phosphatase and Dual-Specificity Protein
Phosphatase PTEN Deficiency; MMAC1 Deficiency; PTEN Tyrosine Phosphatase Deficiency; PTEN1 Deficiency;
NCIt definition : A condition of decreased or absent presence or activity of phosphatidylinositol 3,4,5-trisphosphate
3-phosphatase and dual-specificity protein phosphatase PTEN, which is associated with
multiple hamartoma syndrome (Cowden syndrome) and increased risk for development of
several types of malignant cancers, including head and neck, breast, lung and prostate
cancer and glioblastoma.;
Semantic type(s)