Anti-Globo H Monoclonal Antibody OBI-888NCIt concept
Preferred Label : Anti-Globo H Monoclonal Antibody OBI-888;
NCIt related terms : OBI-888;
NCIt definition : A monoclonal antibody targeting the hexasaccharide glycosphingolipid antigen Globo
H with potential immunostimulating, anti-angiogenic and antineoplastic activities.
Upon infusion, anti-Globo H monoclonal antibody OBI-888 may induce tumor cell destruction
via the activation of antibody dependent cell-mediated cytotoxicity (ADCC), antibody-dependent
cellular phagocytosis (ADCP) and complement-dependent cytotoxicity (CDC), and may
reduce immunosuppression. Globo H is a tumor-associated antigen (TAA) expressed on
the surface of various types of cancer cells.;
UNII : JI5TBH62QP;
CAS number : 2227156-40-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 2227156-40-1
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