Refractory Hepatosplenic T-Cell Lymphoma

Preferred Label : Refractory Hepatosplenic T-Cell Lymphoma;

NCIt definition : Hepatosplenic T-cell lymphoma that is resistant to treatment.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL554300;

Details

Origin ID

C153161;

UMLS CUI

C4727065;

Disease excludes abnormal cell
- Neoplastic B-Lymphocyte [NCIt concept]
- Neoplastic Epithelial Cell [NCIt concept]
- Reed-Sternberg Cell [NCIt concept]
Disease excludes normal cell origin
- Epithelial Cell [NCIt concept]
- Myeloid Cell [NCIt concept]
- Plasma Cell [NCIt concept]
- Precursor Natural Killer Cell [NCIt concept]
- Precursor T-Lymphoblast [NCIt concept]
Disease may have findings
- Aggressive Clinical Course [NCIt concept]
- CD56-Positive Neoplastic Cells Present [NCIt concept]
- Leukocytosis [NCIt concept]
- Thrombocytopenia [NCIt concept]
Excludes anatomical site(s)
- Extrahepatic Bile Duct [NCIt concept]
Has associated anatomic sites
- Digestive System [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
- Hepatobiliary System [NCIt concept]
- Liver [NCIt concept]
- Spleen [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- CD4-Positive Neoplastic Cells Present [NCIt concept]
- CD8-Positive Neoplastic Cells Present [NCIt concept]
disease_excludes_normal_tissue_origin
- Epithelium [NCIt concept]
disease_has_abnormal_cell
- Abnormal Lymphocyte [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
- Neoplastic Lymphocyte [NCIt concept]
- Neoplastic Medium-Sized T-Lymphocyte [NCIt concept]
- Neoplastic T-Lymphocyte and Neoplastic Natural Killer Cell [NCIt concept]
disease_has_finding
- Bone Marrow Involvement [NCIt concept]
- Hepatomegaly [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
- Refractory Disease [NCIt concept]
- Sinusoidal Infiltration [NCIt concept]
- Splenomegaly [NCIt concept]
disease_has_molecular_abnormality
- Clonal T-Cell Receptor Gamma Chain Gene Rearrangement [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Lymphocyte [NCIt concept]
- Peripheral (Post-Thymic) T-Lymphocyte [NCIt concept]
- Peripheral (Post-Thymic) T-Lymphocyte and Natural Killer Cell [NCIt concept]
- T-Lymphocyte and Natural Killer Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
- Hepatobiliary Tissue [NCIt concept]
- Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Digestive System [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
- Hepatobiliary System [NCIt concept]
- Liver [NCIt concept]
- Lymphatic System [NCIt concept]
- Spleen [NCIt concept]
disease_may_have_associated_disease
- Anemia [NCIt concept]
- Hepatitis C Infection [NCIt concept]
disease_may_have_cytogenetic_abnormality
- Trisomy 8 [NCIt concept]
- i(7q) [NCIt concept]
disease_may_have_molecular_abnormality
- Clonal T-Cell Receptor Beta Chain Gene Rearrangement [NCIt concept]
disease_may_have_normal_cell_origin
- Immature Peripheral Alpha/Beta Cell of Cytotoxic Type [NCIt concept]
- Immature Peripheral Gamma/Delta Cell of Cytotoxic Type [NCIt concept]

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