Evocalcet - CISMeF

Preferred Label : Evocalcet;

NCIt synonyms : benzeneacetic Acid, 4-((3S)-3-(((1R)-1-(1-naphthalenyl)ethyl)amino)-1-pyrrolidinyl)-;

NCIt definition : An orally available calcium receptor (CaR) modulator, with potential calcimimetic activity. Upon administration, evocalcet allosterically binds to and inhibits the activity of CaR, thereby suppressing the production of serum parathyroid hormone (PTH) and prevents the PTH-mediated efflux of calcium from bone and normalizes calcium levels.;

UNII : E58MLH082P;

InChIKey : RZNUIYPHQFXBAN-XLIONFOSSA-N;

CAS number : 870964-67-3;

Drug name : Orkedia;

Molecule name : MT-4580; KHK7580;

Chemical formula : C24H26N2O2;

NCI Metathesaurus CUI : CL554363;

Details

Origin ID

C153105;

UMLS CUI

C4519114;

Currated CISMeF NLP mapping
- evocalcet [MeSH concept]
- evocalcet [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- evocalcet [MeSH Supplementary Concept]
- evocalcet [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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