NCIt definition : A long-acting beta-2 adrenergic agonist, with bronchodilator activity. Upon administration,
vilanterol stimulates beta-2 adrenergic receptors in the lungs, thereby activating
the enzyme adenylate cyclase that catalyzes the conversion of adenosine triphosphate
(ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP concentrations
relax bronchial smooth muscle, relieve bronchospasms, and reduce inflammatory cell
mediator release, especially from mast cells.;