Umifenovir - CISMeF

Preferred Label : Umifenovir;

NCIt definition : An orally bioavailable indole derivative, with broad-spectrum antiviral and potential anti-inflammatory activities. Upon oral administration, umifenovir inhibits the fusion of the viral envelope with host cell membrane, thereby blocking the entry of virus into host cells and preventing viral infection and replication. Umifenovir may also suppress the expression of the cytokines interleukin-1beta (IL-1b), IL-6, IL-12 and tumor necrosis factor-alpha (TNF-a) and promote the expression of IL-10. This may reduce inflammation.;

UNII : 93M09WW4RU;

InChIKey : KCFYEAOKVJSACF-UHFFFAOYSA-N;

CAS number : 131707-25-0; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 131707-25-0 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Arbidol;

Details

Origin ID

C152799;

UMLS CUI

C0254211;

Automatic exact mappings (from CISMeF team)
- Umifenovir [ICD-11 Extension code]
Currated CISMeF NLP mapping
- umifenovir [MeSH Supplementary Concept]
- umifenovir [MeSH concept]
- umifenovir [COVID-19 Thesaurus concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- umifenovir [ATC Code]
- umifenovir [MeSH concept]
- umifenovir [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- umifenovir [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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