Sodium Zirconium Cyclosilicate

Preferred Label : Sodium Zirconium Cyclosilicate;

NCIt related terms : Lokelma;

NCIt definition : An insoluble, non-absorbed inorganic material used as a potassium binder and a treatment for hyperkalemia. Upon administration as an oral suspension, sodium zirconium cyclosilicate selectively targets and binds to potassium in the gastrointestinal (GI) tract, exchanging its sodium ions for potassium ions. This increases fecal potassium excretion, decreases the concentration of free potassium in the GI lumen, and lowers serum potassium levels.;

UNII : D652ZWF066;

InChIKey : QMLIRKACNOVYNW-UHFFFAOYSA-N;

CAS number : 17141-74-1;

Drug name : Lokelma;

NCI Metathesaurus CUI : CL553585;

Details

Origin ID

C152381;

UMLS CUI

C4045824;

Currated CISMeF NLP mapping
- Sodium zirconium cyclosilicate (substance) [SNOMED CT concept]
- sodium zirconium cyclosilicate [MeSH concept]
- sodium zirconium cyclosilicate [MeSH Supplementary Concept]
Semantic type(s)
- Inorganic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Sodium zirconium cyclosilicate (substance) [SNOMED CT concept]
- sodium zirconium cyclosilicate [ATC Code]
- sodium zirconium cyclosilicate [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- sodium zirconium cyclosilicate [ATC Code]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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