Risankizumab - CISMeF

Preferred Label : Risankizumab;

NCIt synonyms : Risankizumab-rzaa;

NCIt definition : A humanized immunoglobulin G1 (IgG1) monoclonal antibody targeting the p19 subunit of human interleukin 23 (IL-23) cytokine, with anti-inflammatory activity. Upon administration, risankizumab targets and binds to the p19 subunit of human IL-23, inhibiting the interaction of IL-23 with the IL-23 receptor complex. This inhibits IL-23/IL-23 receptor-mediated signaling and inhibits the release of pro-inflammatory cytokines and chemokines. IL-23 plays an important role in the development, maintenance and activation of Th17 cells, which produce pro-inflammatory cytokines including IL-17A, IL-17F, and IL-22. It is upregulated in various inflammatory and autoimmune diseases.;

UNII : 90ZX3Q3FR7;

CAS number : 1612838-76-2; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 1612838-76-2 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Skyrizi;

Molecule name : ABBV-066; BI-655066;

NCI Metathesaurus CUI : CL773300;

Details

Origin ID

C152227;

UMLS CUI

C4505511;

Automatic exact mappings (from CISMeF team)
- Risankizumab [ICD-11 Extension code]
Currated CISMeF NLP mapping
- Risankizumab (substance) [SNOMED CT concept]
- risankizumab [MeSH concept]
- risankizumab [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing risankizumab (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Product containing risankizumab (medicinal product) [SNOMED CT concept]
- Risankizumab (substance) [SNOMED CT concept]
- risankizumab [MeSH Supplementary Concept]
- risankizumab [ATC Code]
Validated automatic mappings to BTNT
- risankizumab [ATC Code]
chemical_or_drug_has_mechanism_of_action
- Antigen Binding [NCIt concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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