NCIt definition : A narrow-spectrum antibiotic with potential activity against Clostridioides difficile
infection (CDI). Upon oral administration, ridinilazole exerts its bactericidal activity
against C. difficile through inhibition of cell division. This suppresses bacterial
toxin production and inhibits the associated inflammatory response. Compared to other
antibiotics that treat C. difficile, ridinilazole does not deplete intestinal bacteria
and preserves the intestinal bacterial activity and the associated bile acid metabolome.;
Currated CISMeF NLP mapping