Preferred Label : Ribaxamase;
NCIt definition : An orally administered recombinant beta-lactamase that can be used to protect the
gut microbiome from disruption caused by intravenous (IV) administered beta-lactam
antibiotics. Upon administration, ribaxamase hydrolyzes the beta-lactam ring of susceptible
antibiotics that were administered intravenously and are excreted into the intestines.
This degrades the beta-lactam antibiotic, may prevent antibiotic-mediated damage in
the gastrointestinal (GI) tract and may protect the gut microbiome. This may also
prevent the overgrowth and associated infection with Clostridioides difficile and
antibiotic-associated diarrhea. Ribaxamase is not systemically absorbed and does not
interfere with the efficacy of IV beta-lactam antibiotics.;
UNII : 6A002O1K0R;
CAS number : 1792207-66-9;
Molecule name : SYN 004; SYN-004;
NCI Metathesaurus CUI : CL553413;
Origin ID : C152209;
UMLS CUI : C4726690;
Semantic type(s)
- concept_is_in_subset
