NCIt definition : The monohydrate form of relebactam, a beta-lactamase inhibitor, that can be used to
inhibit the breakdown of certain drugs, such as the broad spectrum beta-lactam carbapenem
antibiotic imipenem. Upon administration of relebactam monohydrate, relebactam targets,
binds to and inhibits beta-lactamase. This reduces the breakdown of drugs, such as
imipenem, and thereby increases the activity and therapeutic effect of such drugs
that would otherwise be inactivated by beta-lactamase.;