Mixed Phenotype Acute Leukemia, Rare Types

Preferred Label : Mixed Phenotype Acute Leukemia, Rare Types;

NCIt synonyms : Mixed Phenotype Acute Leukemia, NOS, Rare Subtypes; Mixed Phenotype Acute Leukemia, Rare Subtypes; Mixed Phenotype Acute Leukemia, Not Otherwise Specified, Rare Subtypes;

NCIt definition : A very rare mixed phenotype acute leukemia in which the blasts express combinations of B, T, myeloid, and megakaryocytic lineage markers but are negative for KMT2A rearrangement and t(9;22)(q34;q11.2) translocation. The prognosis is usually unfavorable.;

Neoplastic status : Malignant;

NCI Metathesaurus CUI : CL553211;

Details

Origin ID

C151990;

UMLS CUI

C4726605;

Disease may have findings
- Granulocytopenia [NCIt concept]
- Ineffective Hematopoiesis [NCIt concept]
- Thrombocytopenia [NCIt concept]
- Unfavorable Clinical Outcome [NCIt concept]
Has associated anatomic sites
- Hematopoietic and Lymphatic System [NCIt concept]
Semantic type(s)
- Neoplastic Process [UMLS semantic type]
concept_is_in_subset
- CTRP Disease Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
disease_excludes_finding
- Benign Cellular Infiltrate [NCIt concept]
- Blasts Expressing B-Lymphoid and Myeloid Markers Present [NCIt concept]
- Blasts Expressing CD56 and Immature T-Cell Markers Present [NCIt concept]
- Blasts Expressing T-Lymphoid and Myeloid Markers Present [NCIt concept]
- Chronic Clinical Course [NCIt concept]
- Solid Growth Pattern [NCIt concept]
disease_has_abnormal_cell
- Leukemic Cell [NCIt concept]
- Malignant Cell [NCIt concept]
- Neoplastic Blast [NCIt concept]
- Neoplastic Cell [NCIt concept]
- Neoplastic Hematopoietic and Lymphoid Cell [NCIt concept]
disease_has_finding
- Blasts of Mixed Phenotype Present [NCIt concept]
- Malignant Cellular Infiltrate [NCIt concept]
disease_has_normal_cell_origin
- Hematopoietic and Lymphoid Cell [NCIt concept]
- Multipotent Bone Marrow Stem Cell [NCIt concept]
disease_has_normal_tissue_origin
- Hematopoietic and Lymphoid Tissue [NCIt concept]
disease_has_primary_anatomic_site
- Bone Marrow [NCIt concept]
- Hematopoietic and Lymphatic System [NCIt concept]
disease_may_have_associated_disease
- Anemia [NCIt concept]

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