Preferred Label : Acyclic Nucleoside Phosphonate Prodrug ABI-1968;
NCIt definition : A prodrug of an acyclic nucleoside phosphonate, with potential anti-viral and antineoplastic
activities. Upon administration, acyclic nucleoside phosphonate prodrug ABI-1968 is
taken up by viral-infected cells and converted to its active metabolite. The metabolite
is incorporated into DNA chains by DNA polymerases, which results in the termination
of DNA synthesis, inhibits viral replication and induces apoptosis and inhibits the
proliferation of susceptible virally-infected tumor cells.;
Molecule name : ABI-1968; HTI 1968;
NCI Metathesaurus CUI : CL553169;
Origin ID : C151941;
UMLS CUI : C4726567;
Semantic type(s)
- concept_is_in_subset
