" /> Roquinimex - CISMeF





Preferred Label : Roquinimex;

NCIt synonyms : N-Phenyl-N-methyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxoquinoline-3-carboxamide; 1,2-Dihydro-4-hydroxy-N,1-dimethyl-2-oxo-3-quinolinecarboxanilide;

NCIt related terms : 1,2-Dihydro-4-hydroxy-N,1-dimethyl-2-oxo-N-phenyl-3-quinolinecarboxamide;

NCIt definition : A quinoline-3-carboxamide with potential antineoplastic activity. Roquinimex inhibits endothelial cell proliferation, migration, and basement membrane invasion; reduces the secretion of the angiogenic factor tumor necrosis factor alpha by tumor-associated macrophages (TAMs); and inhibits angiogenesis. This agent is also an immune modulator that appears to alter cytokine profiles and enhance the activity of T cells, natural killer cells, and macrophages. (NCI04);

UNII : 372T2944C0;

InChIKey : SGOOQMRIPALTEL-UHFFFAOYSA-N;

CAS number : 84088-42-6; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 84088-42-6 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Linomide;

Molecule name : FCF 89; LS 2616;

Chemical formula : C18H16N2O3;

Codes from synonyms : 09087;

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09/05/2024


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