PTP4A3 wt Allele

Preferred Label : PTP4A3 wt Allele;

NCIt synonyms : PRL-R; PRL-3; Protein Tyrosine Phosphatase Type IVA, Member 3 wt Allele; Protein Tyrosine Phosphatase, Type 4A, 3 Gene; PRL3; Protein-Tyrosine Phosphatase, Type 4A, 3 Gene;

NCIt definition : Human PTP4A3 wild-type allele is located in the vicinity of 8q24.3 and is approximately 40 kb in length. This allele, which encodes protein tyrosine phosphatase type IVA 3 protein, is involved in protein phosphatase activity, progression of the cell cycle and promotion of cell proliferation and cell motility. Aberrant expression of the gene is associated with tumor metastasis.;

NCI Metathesaurus CUI : CL553237;

GenBank Accession Number : AF041434;

Details

Origin ID

C151405;

UMLS CUI

C4723884;

Automatic exact mappings (from CISMeF team)
- Prolactin receptor [OMIM gene]
- Protein-tyrosine phosphatase, type 4a, 3 [OMIM gene]
- Submaxillary gland androgen-regulated protein 3b [OMIM gene]
- prolactin receptor [ORDO Gene]
OMIM relation
- Protein-tyrosine phosphatase, type 4a, 3 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 8q24.3 [NCIt concept]
gene_is_element_in_pathway
- PTP4A Family Signaling Pathway [NCIt concept]
gene_plays_role_in_process
- Cell Differentiation Process [NCIt concept]
- Cell Growth [NCIt concept]
- Cell Migration Induction [NCIt concept]
- Cell Proliferation [NCIt concept]
- Dephosphorylation [NCIt concept]
- G1 to S Transition Process [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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