Radioimmunoconjugate

Preferred Label : Radioimmunoconjugate;

NCIt synonyms : Radiolabeled Antibodies;

NCIt definition : Monoclonal antibodies (MoAb) conjugated with radioisotopes, i.e., I-131, Y-90, T-99, or In-111. Using radioimmunoconjugates in radiotherapy or radioimaging has the advantage of targeting cells carrying specific antigens, thereby limiting toxic effects on normal cells. Tumor eradication can be achieved by either the antibody-mediated immune response or by only the cytotoxic activity of the radiation.;

Details

Origin ID

C1511;

UMLS CUI

C0243019;

Currated CISMeF NLP mapping
- radioimmunoconjugates [MeSH concept]
Semantic type(s)
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- radioimmunoconjugates [MeSH concept]
Validated automatic mappings to NTBT
- immunoconjugates [MeSH Descriptor]

Keyword's position in hierarchy(ies) :

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