Homologous Recombination Repair Biallelic Inactivation

Preferred Label : Homologous Recombination Repair Biallelic Inactivation;

NCIt synonyms : HHR Biallelic Inactivation; Recombination Repair Biallelic Inactivation; HRR Biallelic Inactivation; Homologous Recombination Pathway Biallelic Inactivation;

NCIt definition : The presence of mutations in both alleles of a gene involved in homologous recombination-type DNA repair that lead to defects in DNA repair pathways.;

NCI Metathesaurus CUI : CL552387;

Details

Origin ID

C150641;

UMLS CUI

C4725894;

Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
molecular_abnormality_involves_gene
- DNA Repair Gene [NCIt concept]
- Homologous Recombination Repair Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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