Activating FLT3 Gene Mutation

Preferred Label : Activating FLT3 Gene Mutation;

NCIt synonyms : Activating FLK2 Gene Mutation; Activating FMS-Related Tyrosine Kinase 3 Gene Mutation; Activating CD135 Gene Mutation; Activating FLT3 Gene Mutant; FLT3 Activating Mutation;

NCIt definition : A change in the nucleotide sequence of the FLT3 gene that that results in constitutive activation of receptor-type tyrosine-protein kinase FLT3 and its downstream signaling pathways.;

NCI Metathesaurus CUI : CL552305;

Details

Origin ID

C150623;

UMLS CUI

C4725879;

Molecular abnormality of diseases
- Early T Precursor Acute Lymphoblastic Leukemia [NCIt concept]
- Early T Precursor Acute Lymphoblastic Leukemia with BCL11B Rearrangement [NCIt concept]
- Early T Precursor Acute Lymphoblastic Leukemia, Not Otherwise Specified [NCIt concept]
- Early T Precursor Lymphoblastic Leukemia/Lymphoma [NCIt concept]
Semantic type(s)
- Cell or Molecular Dysfunction [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Disease Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_mutant_encodes_gene_product_sequence_variation
- FLT3 Protein Variant [NCIt concept]
molecular_abnormality_involves_gene
- FLT3 Gene [NCIt concept]
- Receptor Tyrosine Kinase Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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