NCIt synonyms : Candida albicans Test Antigen Injection; Candida albicans Skin Test Antigen;
NCIt definition : An injectable formulation composed of antigens derived from the culture filtrate and
cells of two different strains of Candida albicans (C. albicans), with immunomodulatory
activity. Upon intralesional administration into the cutaneous human papilloma virus
(HPV)-infected warts, the C. albicans antigens stimulate the immune system to mount
a cytotoxic T-lymphocyte (CTL)-mediated immune response against the injected antigens
and cause a delayed type hypersensitivity response against other local antigens, including
antigens within the wart tissue. This leads to the production of Th1 cytokines, and
the activation of natural killer (NK) cell- and CTL- mediated killing of HPV-infected
cells. This causes clearing of both local and distant warts, and prevents both HPV
infection and wart formation that results from HPV infection.;
Currated CISMeF NLP mapping