Licogliflozin - CISMeF

Preferred Label : Licogliflozin;

NCIt synonyms : D-Glucitol, 1,5-Anhydro-1-C-(3-((2,3-dihydro-1,4-benzodioxin-6-yl)methyl)-4-ethylphenyl)-, (1S)-;

NCIt definition : An inhibitor of the sodium-dependent glucose co-transporter (sodium-glucose transporter; sodium-glucose transport protein; sodium-glucose linked transporter; SGLT) family members 1 and 2 (SGLT1/2) with antihyperglycemic activity. By binding to and blocking SGLT1/2, licogliflozin suppresses the reabsorption of glucose in the proximal tubule within the kidneys and enhances urinary excretion of glucose. This normalizes blood glucose levels. SGLT1/2, parts of a transport system expressed in the proximal renal tubules, mediate the majority of renal glucose reabsorption from tubular fluid.;

UNII : 57J06X6EI0;

InChIKey : XFJAMQQAAMJFGB-ZQGJOIPISA-N;

CAS number : 1291094-73-9;

Molecule name : LIK-066; LIK 066;

NCI Metathesaurus CUI : CL552172;

Details

Origin ID

C150375;

UMLS CUI

C4725688;

Automatic exact mappings (from CISMeF team)
- licogliflozin [MeSH concept]
- licogliflozin [MeSH Supplementary Concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- licogliflozin [MeSH Supplementary Concept]
concept_is_in_subset
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]

Keyword's position in hierarchy(ies) :

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