Gelsolin - CISMeF

Preferred Label : Gelsolin;

NCIt synonyms : AGEL; Actin-Depolymerizing Factor; GSN; ADF; Brevin;

NCIt definition : Gelsolin (782 aa, 86 kDa) is encoded by the human GSN gene. This protein is involved in the modulation of actin filament polymerization.;

NCI Metathesaurus CUI : CL552043;

Details

Origin ID

C150253;

UMLS CUI

C4723803;

Automatic exact mappings (from CISMeF team)
- Destrin [OMIM gene]
- Gelsolin [OMIM gene]
- Gelsolin [FMA entity]
- Gelsolin (substance) [SNOMED CT concept]
- actin depolymerizing factors [MeSH Descriptor]
- brevin [MeSH concept]
- brevin [MeSH Supplementary Concept]
- gelsolin [ORDO Gene]
- gelsolin [HGNC gene]
- gelsolin [MeSH concept]
- gelsolin [SNOMED Notion]
- gelsolin [MeSH Descriptor]
OMIM relation
- Gelsolin [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- Cytoskeletal Gene [NCIt concept]
- GSN Gene [NCIt concept]
- Structural Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoskeleton [NCIt concept]
gene_product_has_biochemical_function
- Actin-Binding Protein [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Caspase Cascade in Apoptosis [NCIt concept]
- Coregulation Pathway for Androgen Receptor Activity [NCIt concept]
- Extracellular Matrix Binding Pathway [NCIt concept]
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- HIV-I Nef in Apoptosis Pathway [NCIt concept]
- N-Cadherin Signaling Pathway [NCIt concept]
- Osteopontin-Mediated Signaling Pathway [NCIt concept]
- Rho Cell Motility Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Movement Process [NCIt concept]
- Cytoskeletal Modeling [NCIt concept]
- Cytoskeletal Process [NCIt concept]
- Regulation of Cell Shape [NCIt concept]

Keyword's position in hierarchy(ies) :

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