NCIt definition : The ethyl ester form of telotristat, a tryptophan hydroxylase (TPH) inhibitor, with
potential anti-serotonergic activity. Upon administration, telotristat binds to and
inhibits the activity of TPH. This may result in a reduction in peripheral serotonin
(5-HT) production and improvement of serotonin-mediated gastrointestinal effects such
as severe diarrhea. TPH, the rate-limiting enzyme in serotonin biosynthesis, is overexpressed
in carcinoid tumor cells.;
UNII : 8G388563M7;
InChIKey : MDSQOJYHHZBZKA-GBXCKJPGSA-N;
CAS number : 1033805-22-9;
Molecule name : LX-1032; LX-1606; LX 1032; LX 1606;
Currated CISMeF NLP mapping