" /> Satraplatin - CISMeF





Preferred Label : Satraplatin;

NCIt synonyms : (OC-6-43)-bis(acetato)amminedichloro(cyclohexylamine)platinum; (OC-6-43)-bis(acetato-O)amminedichloro(cyclohexanamine)platinum; platinum,bis(acetato-O)amminedichloro(cyclohexanamine)-,(OC-6-43);

NCIt related terms : BMS-182751; JM 216;

NCIt definition : An orally administered third generation platinum compound with potential antineoplastic activity. Satraplatin forms highly reactive, charged, platinum complexes which bind to nucleophilic groups in DNA, inducing intrastrand and interstrand DNA cross-links, as well as DNA-protein cross-links. These cross-links result in cell growth inhibition and apoptosis.;

Alternative definition : NCI-GLOSS: A substance being studied in the treatment of prostate and other types of cancer. It contains the metal platinum and may kill cancer cells by damaging their DNA and stopping them from dividing. It is a type of alkylating agent.;

UNII : 8D7B37T28G;

InChIKey : QFDCPOONOIIAOS-UHFFFAOYSA-J;

CAS number : 129580-63-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 129580-63-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Drug name : Orplatna;

Molecule name : BMY-45594; JM-216;

Chemical formula : C6H13N.2C2H3O2.2Cl.Pt.H3N;

Codes from synonyms : CDR0000367461; CDR0000045425; CDR0000367462;

Details


Keyword's position in hierarchy(ies) : arborescence

You can consult :


Nous contacter.
12/05/2024


[Home] [Top]

© Rouen University Hospital. Any partial or total use of this material must mention the source.