GRHPR wt Allele

Preferred Label : GRHPR wt Allele;

NCIt synonyms : GLYD; Glyoxylate and Hydroxypyruvate Reductase wt Allele; MSTP035; Glycerate-2-Dehydrogenase Gene; PH2; GLXR; Primary Hyperoxaluria Type 2 Gene;

NCIt definition : Human GRHPR wild-type allele is located in the vicinity of 9p13.2 and is approximately 14 kb in length. This allele, which encodes glyoxylate reductase/hydroxypyruvate reductase protein, plays a role in hydroxypyruvate and glyoxylate metabolism. Mutation of the gene is associated with type II primary hyperoxaluria.;

NCI Metathesaurus CUI : CL551160;

GenBank Accession Number : AF134895;

Details

Origin ID

C148629;

UMLS CUI

C4723657;

Automatic exact mappings (from CISMeF team)
- Glyoxylate reductase/hydroxypyruvate reductase [OMIM gene]
- Primary hyperoxaluria type 2 [ORDO Disease]
- glyoxylate and hydroxypyruvate reductase [ORDO Gene]
OMIM relation
- Glyoxylate reductase/hydroxypyruvate reductase [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_found_in_organism
- Human [NCIt concept]
gene_is_element_in_pathway
- Glycine, Serine and Threonine Metabolism Pathway [NCIt concept]
- Glyoxylate and Dicarboxylate Metabolism Pathway [NCIt concept]
- Pyruvate Metabolism Pathway [NCIt concept]
gene_plays_role_in_process
- Intermediary Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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